ZFIN Image: Pfefferli et al., 2017, Fig. S6

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Figure Caption

Fig. S6

Treatment of uninjured organs with the inhibitor of TGFβ/Activin-β signalling does not affect the homeostatic expression of careg:EGFP.

(a) Experimental design. Uninjured fish were treated with the inhibitor of TGFβ/Activin-β (20 μM SB431542) for 7 days. (b-c) Immunofluorescence staining of uninjured ventricles after 7 days of SB431542 treatment. The expression of careg:EGFP in the subcortical layer is similar in control and treated fish. (d-e) Longitudinal sections of rays in uninjured fins. Osteoblasts are marked with Zns5 antibody (red). They cover the surface of acellular bone matrix. In both control and treated specimens, careg:EGFP is expressed in intraray osteoblasts, in a few scattered MES and the artery. EP, epidermis; MES, mesenchyme; B, accelular bones. N=4.

Acknowledgments

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