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Fig. 7

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ZDB-IMAGE-170512-30
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Figures for Berberoglu et al., 2017
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Fig. 7

A subset of Rbfox2-expressing cells are myog:H2B-mRFP-positive during skeletal muscle repair. (A) Injury time-course experiment performed in myog:H2B-mRFP transgenic line showing Rbfox2 expression (on alternating sections with those described in Fig. 6). (B) As shown in Fig. 6B, myog:H2B-mRFP expression is readily observed within the injury site by 4 dpi. (C) Overlay of Rbfox2 and myog:H2B-mRFP expression. (D) Total number of Rbfox2, myog:H2B-mRFP double-positive cells at 2–7 dpi. (E) Ratio of Rbfox2-positive cells that are myog:H2B-mRFP-positive at 2–7 dpi. One-way ANOVA followed by Tukey's multiple comparisons test was performed for all of the above statistical analyses; differences among time-points are not statistically significant. (F-H) Higher magnification view of 4 dpi injury site shown in A-C. (F’-H’) Area shown is the boxed region in F-H that highlights examples of Rbfox2-expressing cells that are myog:H2B-mRFP-positive (white arrowheads) and myog:H2B-mRFP-negative (blue arrowheads). Scale bar in all panels is 75 µm.

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Reprinted from Developmental Biology, 424(2), Berberoglu, M.A., Gallagher, T.L., Morrow, Z.T., Talbot, J.C., Hromowyk, K.J., Tenente, I.M., Langenau, D.M., Amacher, S.L., Satellite-like cells contribute to pax7-dependent skeletal muscle repair in adult zebrafish, 162-180, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.