ZFIN Image: Yuan et al., 2015, Fig. 4

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Fig. 4

Loss of cebpa leads to enhanced hepatic cell proliferation and subsequent increased apoptosis.

(A-H) Hepatic cell proliferation and apoptosis were determined by pH3 staining and TUNEL assay in 60 and 72 hpf embryos, respectively. The sections were counterstained with DAPI to label the nucleus. Dashed lines circle the boundary of the liver. White arrows indicate pH3 or TUNEL positive cells, respectively. In each case or at each time-point, more than 5 sections from at least three sibling control or cebpa mutant fish were examined. (I) intestine. (I,J) Quantification of hepatic cell proliferation and apoptosis, respectively. Data shown are the mean ± SD, n ≥ 3, *P < 0.05 by student’s t-test.

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Phenotype details

Acknowledgments

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