IMAGE
Fig. 2
Image
|
Figure Caption
Fig. 2
Photoreceptors and projection neurons are not maintained in the pineal complex of med12 mutants. Rod photoreceptors were absent at 4 dpf in med12 mutants, as labeled by immunofluorescence for 4c12 (A, A′) and Opsin1 (B, B′). Cone cells are also absent in med12 mutants at 4 dpf, as shown by Arr3a staining (C, C′). Elavl3 staining showed a reduction in the number of the projection neurons at 4 dpf (D, D′). med12 mutants and WT showed comparable expression of the TgBAC[flh:kaede] transgene (E, E′), which labels the pineal complex at 1 dpf. Cell nuclei are stained with ToPro3 (blue).
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 385(1), Wu, S.Y., de Borsetti, N.H., Bain, E.J., Bulow, C.R., and Gamse, J.T., Mediator subunit 12 coordinates intrinsic and extrinsic control of epithalamic development, 13-22, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.