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Fig. 4

ID: ZDB-IMAGE-160707-6
Publication: Davuluri et al., 2016 - Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy
All Figures: Figures for Davuluri et al., 2016

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Fig. 4

Bdh2-inactivated erythrocytes contain mitochondria in autophagosomal vesicles. (A) Representative EM images of erythrocytes isolated from control and bdh2 morphants. Arrows indicate autophagosomal vesicles. Arrowheads indicate lysosomal vesicles. (Scale bars: 1 µM.) Area in rectangle is enlarged. (Scale bar: Inset, 100 nM.) (B) Total mitochondria count per cell counted by EM. Data are mean ± SD for 50 cells. P < 0.05 was considered significant. (C) Confocal fluorescent imaging of LysoTracker- and MitoTracker-stained erythrocytes isolated from control and bdh2 morphants or bdh2-overexpressing bdh2 morphants. Arrowheads indicate costained cells. Representative images are depicted.

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