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Fig. 10
In vivo nano-xenotoxicity assessment and intravital imaging in 3 dpf zebrafish embryos.(A) Bright-field microscopic images of 3 dpf zebrafish embryos (N = 25) treated with optimized concentrations of MUA-functionalized CIZS-NCs for 3.0 h. (B) CYP1A and SOD2 gene expression profile in embryos incubated with 7.8 µg/ml concentration of MUA-functionalized CIZS-NCs. (C) Bright-field (a,c,e,g) and fluorescence (b,d,f,h) microscopic images of 3 dpf zebrafish embryos co-incubated with optimized concentrations of MUA-functionalized CIZS-NCs at 3.0 h.
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