ZFIN Image: Ohnmacht et al., 2016, Fig. 4

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Figure Caption

Fig. 4

Motor neuron regeneration is enhanced by application of a dopamine agonist. (A) Experimental time line. (B,C) Double-labelled Hb9:GFP⁺/EdU⁺ neurons are indicated by arrowheads. (B′-C′′′) Double-labelled cells from B,C (asterisks) are indicated by arrowheads in single optical sections at higher magnification. (D) Pergolide treatment during the regeneration phase significantly increases the number of Hb9:GFP⁺/EdU⁺ double-labelled motor neurons (t-test, **P=0.0092; DMSO, n=12; Pergolide, n=9). Lateral views are shown; rostral is left, dorsal is up. The lesion site is indicated by a dashed line. Values are means ± s.e.m. Scale bars: 50µm in B for B,C; 10µm in B′′′ for B′-C′′′.

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