ZFIN Image: Abrams et al., 2016, Fig. 6

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Figure Caption

Fig. 6

Zebrafish myh11 mutations alter intestinal transit. (A,B) Intestinal transit as measured by the expulsion of fluorescent microspheres in wild-type and sibling homozygous mlt larvae injected with a myh11 morpholino (MO) (A), and wild-type and sibling S237Y homozygous larvae (B). Anterior: beads remain in anterior intestinal bulb; posterior: beads remain in mid- and posterior intestine; expelled: no beads remaining in the intestine. ****P<0.001. Chi-squared test performed with 2 degrees of freedom. (C) Time lapse of a wild-type (WT) larva beginning when the fluorescent beads are present in the anterior intestine and followed until bead expulsion. A, M, P, location of anterior intestine, mid-intestine and posterior intestine, respectively.

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Acknowledgments

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