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Fig. 6
Decreased proliferation following appb knockdown. Whole-mount immunostaining of embryos at 24 hpf (A-B). Confocal images (anterior at the top) of hindbrain stained with pH3 (green) and DAPI (blue) in control (A) and appb MO-injected (B) embryos. Bar graph displays the quantification of dividing cells (C). Scale bar, 50 µm. ****p<0.0001.
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Reprinted from Developmental Biology, 413(1), Banote, R.K., Edling, M., Eliassen, F., Kettunen, P., Zetterberg, H., Abramsson, A., β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner, 26-38, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.