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Fig. S3
Cell death analysis in appb morphants.
Acridine orange (AO)-labeled embryos at 48 hpf (A-B). Confocal images (anterior at the top) of hindbrain labeled with acridine orange (AO) in control MO (A) and appb MO-injected (B) embryos at 48 hpf. Bar graph displays the quantification of AO positive cells (C). Scale bar, 50 µm. ****p < 0.0001
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Reprinted from Developmental Biology, 413(1), Banote, R.K., Edling, M., Eliassen, F., Kettunen, P., Zetterberg, H., Abramsson, A., β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner, 26-38, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.