ZFIN Image: Zhang et al., 2016, Fig. 3

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Figure Caption

Fig. 3

Ganciclovir inhibits MGPC proliferation. (A) Schematic illustration showing the experimental timeline. Retinas of wild-type zebrafish were injured, and all fish received a pulse of BrdU at 45 hpi. Fish then received intravitreous PBS or GCV injection once daily until 4 dpi. Retinas were collected at indicated time points (48, 72, and 96 hpi). (B) Bromodeoxyuridine immunofluorescence showing that GCV inhibits the expansion of MGPCs in the retina. Bromodeoxyuridine signals are shown in green. (C) Quantification of (B). *P < 0.05 compared to PBS-treated control. n = 3 for each group. Scale bars: 100 µm. The asterisks mark the injury site (needle poke).

Acknowledgments

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