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Fig. 5
Expression of Alcam in AV endocardial cells is expanded in id4 mutants. Alcam positive AV endocardial cells (yellow) were found to be increased in id4 mutants (B) as compared to their id4 heterozygous siblings (A) at 52 hpf. (C) Quantification of Alcam positive AV endocardial cells. (A, Atrium; AVC, Atrioventricular Canal; V, Ventricle; SAV, Superior AVC; IAV, Inferior AVC). Scale bars, 20 µm. p-value **- 0.0016, *- 0.0114. (Green – Alcam; Red - Tg(kdrl:ras-mCherry).
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Reprinted from Developmental Biology, 412(1), Ahuja, S., Dogra, D., Stainier, D.Y., Reischauer, S., Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development, 71-82, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.