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Fig. S1
Conditional expression of Tg(hsp70:lh3myc) rescues lh3 motor axon guidance defects, related to Figures 2 and 3.
(A) Schematic showing conditional expression paradigm.
(B) Tg(hsp70:lh3myc) is no longer detectable by western blot at 4 dpf.
(C,D) Schematics showing patterns of dorsal and ventral motor axon outgrowth detected in (E-G) and (H-J) with Tg(isl1:gfp) and Tg(mnx1:gfp) respectively.
(E-G) Dorsal (72hpf) and (H-J) ventral (52hpf) motor axon development was rescued by expression of Tg(hsp70:lh3myc) (n > 20 larvae, 200 nerves per condition). Red arrowheads show misguided mutant axons.
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