ZFIN Image: Burgoyne et al., 2015, Fig. 1

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Figure Caption

Fig. 1

OA1 MOs reduce melanosome number at 2dpf without affecting melanosome size. (A–D) Contrast-enhanced images of zebrafish eye cross-sections highlighting only electron-dense melanin. Images are shown from (A,B) control and (C,D) OA1 MO-treated zebrafish. KD, knockdown. Scale bars: 20µm. (E) At 2dpf there is a significant reduction in melanin area between controls and OA1 MO-treated zebrafish. By 5dpf, the OA1 MO appears to be less effective, resulting in no significant difference in melanin area between controls and OA1 MO-treated animals. (F) The OA1 MO had no apparent effect on melanosome diameter at 2 and 5dpf. Results show the mean±s.e.m.; *P<0.05 (Student′s t-test).

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.