ZFIN Image: Ma et al., 2015, Fig. 4

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Figure Caption

Fig. 4

fgf10a RNA levels are specifically reduced at the posterior prosensory domain in jag1b^-/- embryos. (A-F) Whole-mount in situ hybridization of jag1b^+/+, jag1b^+/- and jag1b^-/- embryos at 30 and 34hpf. Lateral views. Scale bar: 20µm. (G-H′′) Posterior cristae in jag1b^+/- embryos treated with DMSO (G-G′′) or SU5402 (H-H′′) at 24-26hpf. Dorsolateral views. Scale bars: 50µm in G-H′; 10µm in G′′ and H′′. (I) TUNEL staining of jag1b^+/- embryos treated with DMSO or SU5402. Apoptosis signals are detected in the posterior prosensory domain of the SU5402-treated jag1b^+/- embryos at 42hpf. Dorsolateral views. Scale bars: 40µm (left) and 20µm (right). (J) Phalloidin staining of jag1b^+/- embryos treated with DMSO or SU5402. Lateral views. Scale bar: 50µm. Anterior towards the left and dorsal upwards. Boxed regions are enlarged on the right. Arrows and arrowheads indicate posterior crista regions.

Figure Data

Expression / Labeling details

Acknowledgments

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