Fig. 11
- ID
- ZDB-IMAGE-150318-4
- Antibodies
- Publication
- Rajaram et al., 2014 - Dynamic miRNA Expression Patterns During Retina Regeneration in Zebrafish: Reduced Dicer or miRNA Expression Suppresses Proliferation of Müller Glia-Derived Neuronal Progenitor Cells
- All Figures
- Figures for Rajaram et al., 2014
Fig. 11 Knockdown of miR-2190 does not affect proliferation. Adult albino zebrafish were intravitreally injected and electroporated with either standard control or miR-2190 morpholino prior to the start of light damage. A,B: After 51h of constant light, standard control and miR-2190 morphant retinas both display PCNA-positive doublet INL proliferating nuclei (arrows). C,D: After 72h of light, standard control and miR-2190 morphant retinas display clusters of INL nuclei (arrowheads). E,F: Statistically equivalent numbers of INL and ONL PCNA-positive nuclei are present in standard control and miR-2190 morphant retinas. INL, inner nuclear layer; ONL, outer nuclear layer. Scale bar in A = 50 µm and applies to B–D; data represent mean ± s.e.m. P > 0.05 using two-way ANOVA with Tukey′s post-hoc test, n=6.