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Figure Caption
Fig. 5 Nodal signaling is required to maintain osr1 expression. A-C: Animal pole views. At 5 hpf (A, A′, A′′) osr1 is expressed in the margin of the embryo. Embryos treated with 50 µM SB505124 from 5 hpf to 6.5 hpf show a dramatic reduction in levels of osr1 mRNA (C, C′, C′′) as compared to DMSO-treated controls (B, B′, B′′) indicating that osr1 mRNA is degraded in the absence of Nodal signaling.
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