ZFIN Image: Giustiniani et al., 2014, Fig. S2

Image

Figure Caption

Fig. S2 FKBP52 is expressed ubiquitously in the nervous system in zebrafish. (A) Sequence alignment of Danio rerio (Z) and human (H) FKBP52. D. rerio FKBP52 amino acid sequence shares 62% of identities (amino acids in red) and 83% of homologies with the human ortholog. Based on the 3D structure of human FKBP52 (1), four domains are delineated. The single underlining indicates peptidyl-prolyl isomerase (PPIase) and FK506-binding domain, the double underlining indicates PPIase-like domain, the thick underlining indicates tetratricopetide repeat domain, and the dashed underlining indicates calmodulin binding domain. (B) RT-PCR shows the expression of FKBP52 during development. NCtrl, negative control. (C) Whole-mount FKBP52 in situ hybridization shows its maternal ubiquitous expression [1.25 h postfertilization (hpf)] that persists until 32 hpf. (Scale bars: 200 µm.)

Figure Data

Expression / Labeling details

Acknowledgments

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