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Figure Caption
Fig. 5 AD0157 inhibits angiogenesis in vivo. (A) Chorioallantoic membrane assay (CAM). The methylcellulose disc containing the substance vehicle alone and the methylcellulose disc containing 0.5, one and 5 nmol of AD0157. Circles show the locations of the methylcellulose discs (bar = 1 mm); (B) Inhibition of the zebrafish neovascularization by AD0157. Transgenic TG(fli1:EGFP)y1 zebrafish embryos that show green fluorescent protein (GFP) expression in endothelial cells were incubated without or with 10 μM AD0157 (bars represent 50 μm).
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