ZFIN Image: He et al., 2014, Fig. 1

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Figure Caption

Fig. 1

Maternal Vsx1 is essential for axial–paraxial mesoderm patterning in zebrafish. (A–C) Uninjected wild-type control embryos. (D–F) vsx1 tbMO injected embryos exhibit dorsalized phenotype with disturbed dorsal midline structure. (G–I) vsx1 overexpression elicits inhibition of axial mesoderm specification and aberrant convergence of specified paraxial mesoderm. (J–L) Injection of vsx1 sbMO has no detectable effect on development before 24 hpf. Phenotypes are shown at 24 hpf. (M) Proportion of different phenotypes in vsx1 knockdown, overexpression and rescue experiments at 24 hpf. DDMS: disorganized dorsal midline structure. SB: spina bifida.

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Phenotype details

Acknowledgments

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Reprinted from Developmental Biology, 386(1), He, Y., Xu, X., Zhao, S., Ma, S., Sun, L., Liu, Z., and Luo, C., Maternal control of axial-paraxial mesoderm patterning via direct transcriptional repression in zebrafish, 96-110, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.