ZFIN Image: Sittaramane et al., 2013, Fig. 1

Image

Figure Caption

Fig. 1 FBM neurons contact vangl2-expressing floor plate cells in rhombomere 4. (A,D) Dorsal views of Tg(islet1:GFP) hindbrains processed for vangl2 in situs (purple) and anti-GFP immunostaining to label FBM neurons (brown). The level of the cross-sections is indicated by the broken lines. (B,E) vangl2 is expressed broadly in the endoderm, mesoderm and within the neural tube, including the floor plate (fp, black arrowhead). Some FBM neurons (white arrowhead) are immediately adjacent to the floor plate cells. (C,F) FBM neuron cell bodies and processes (white arrowhead) contact floor plate cells marked by shh expression (purple). n, notochord; oto, otocyst.

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Expression / Labeling details

Acknowledgments

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Reprinted from Developmental Biology, 382(2), Sittaramane, V., Pan, X., Glasco, D.M., Huang, P., Gurung, S., Bock, A., Li, S., Wang, H., Kawakami, K., Matise, M.P., and Chandrasekhar, A., The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function, 400-412, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.