ZFIN Image: Storer et al., 2013, Fig. 2

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Figure Caption

Fig. 2 Zebrafish injected with rag2:KRAS^G12D, cdh15:KRAS^G12D or mylz2:KRAS^G12D develop muscle tumors that differ in histological appearance. (A-C) Brightfield images of fish bearing rag2 (A), cdh15 (B) and mylz2 (C) tumors. (D-G) H&E staining of tumors. (H-W) Tumors express diagnostic markers of RMS as assessed by RNA in situ hybridization. Histological sections of representative rag2 (D,H,L,P,T), cdh15 (E,I,M,Q,U) and mylz2 (F,J,N,R,V) tumors and normal muscle (G,K,O,S,W). Images in D-W are at the same magnification. (X) Tumors were assigned differentiation scores based on histological appearance. Scale bars: in A-C, 2 mm; in D-G, 50 μm.

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