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Fig. S5

ID: ZDB-IMAGE-130719-16
Publication: Mahmood et al., 2013 - Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome
All Figures: Figures for Mahmood et al., 2013

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Fig. S5 Kcnj10a knockdown does not cause off-target effects or significant anatomical changes to the nervous system. Immunohistochemistry for anti-acetylated α tubulin at 120 hpf reveals axons and dendrites and labels the cerebellar plate (cp in A), retinal ganglion cells (rgc in E), ganglia of otic vesicle (ov in E), lateral line (arrow in I) and motor axons (arrow in M). Comparison of wildtype (A, E, I and M) to kcnj10a morphants (B, F, J and N), kcnj10a and p53 double morphants (C, G, K and O), and p53 morphants (D, H, L P) reveals no significant differences in these structures. Scale bar=100 μm.

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