ZFIN Image: Stoletov et al., 2013, Fig. S6

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Figure Caption

Fig. S6

Inhibition of Cx26 expression in b16 melanoma cells inhibits GJ communication with the endothelium. (A) b16 metastatic melanoma cells expressing the empty lentiviral vector (b16 control) or b16 cells stably expressing lentiviral shRNAs to Cx26 (b16KNcx26) were western blotted for the indicated proteins. (B) b16 control and b16KNcx26 cells were tested for their ability to transfer calcein orange dye to the endothelium as described in Fig. S2B. * = P values < 0.05 (C) The indicated tumor cells were cultured in vitro and examine for cell growth after 3 days in the presence of CBX or its vehicle using the CyQUANT assay. rfu = relative florescence units.

Acknowledgments

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