Fig. 8 nf1 mutants display decreased lateral stripe melanophores. (A-D) Lateral stripe melanophores of wild-type (A,B) larvae demonstrate a normal uniform pattern that is absent in nf1a-/-; nf1b-/- larvae (C,D) at 6 dpf. The brackets in D highlight regions where melanophores are absent. (E) Quantification of lateral stripe melanophores from wild-type (n=26), nf1a+/-; nf1b-/- (n=30), nf1a-/-; nf1b+/+ (n=14), nf1a-/-; nf1b+/- (n=26) and nf1a-/-; nf1b-/- (n=12) larvae at 6 dpf. Each point represents the number of lateral stripe melanophores in an individual embryo and red lines indicate mean values. *P<0.05, **P<0.01. Scale bars: 0.5 mm (A,C) and 150 μm (B,D).
Image
Figure Caption
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Dis. Model. Mech.