ZFIN Image: Ichimura et al., 2012, Fig. 3

Image

Figure Caption

Fig. 3 Temporal specification of the three glomerular components during glomerular development in zebrafish.

A1-A4: wt1a mRNA is expressed in the forming glomerulus from 34 hpf to 4 dpf. Cross sections show wt1a-positive podocyte layers of the paired glomeruli at 34 hpf (A1). Unlike medaka, zebrafish wt1a-positive podocytes are merged at 2 dpf (A2). B1-B4: Glomerular capillaries are detected by AP stain. At 34 hpf, the flattened nephron primordia show proximity to the dorsal aorta (B1). Glomerular capillaries are found at 2 dpf (B2). Dorsal aorta (arrows in B1-B4). C1-C4: GBM and mesangial matrix are detected by PAM stain. The paired glomeruli fuse at the midline and the interglomerular mesangium is not formed (C2-C4). Scale bars = 10 μm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One