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Fig. 4
sox9b early hepatopancreatic expression is activated by FGF and BMP and is maintained in the ducts by FGF and Notch. (A, B) sox9b early expression (30 hpf) in the hepatic and ventral pancreatic primordia (HVP) is not activated in compound fgf10; fgf24 mutants (C, D) Similarly, sox9b is not induced in bmp2a morphants. Note that sox9b in the dorsal pancreatic bud (DP) is not affected.
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Reprinted from Developmental Biology, 366(2), Manfroid, I., Ghaye, A., Naye, F., Detry, N., Palm, S., Pan, L., Ma, T.P., Huang, W., Rovira, M., Martial, J.A., Parsons, M.J., Moens, C.B., Voz, M.L., and Peers, B., Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration, 268-278, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.