ZFIN Image: Prendergast et al., 2012, Fig. S6

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Figure Caption

Fig. S6

The neural crest of sdp embryos migrates to its normal extent. (A-B) Migrating streams of neural crest as seen in a 24 hpf sox10:eos transgenic background. Somites are immunostained for MF20 (A). Scale bar: 250 μm. The neural crest signal (green) was thresholded (A2) and dorsoventral migration distance was measured across the rostrocaudal axis using a MatLab algorithm (B) (blue line). The raw migration data were smoothed by averaging (black line) and local maxima were detected by iterative point-to-point comparison (red circles). (C-D) sdp^w12/w12 embryos exhibit neural crest that appears to migrate the appropriate distance. (E) Neural crest migration distance at 24 hpf is indistinguishable across all three sdp^w12 genotypes. White circles, sdp^+/+; gray circles, sdp^w12/+; black circles, sdp^w12/w12. Error bars represent s.d.

Acknowledgments

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