ZFIN Image: Patten et al., 2012, Fig. 3

Image

Figure Caption

Fig. 3 Knockdown of chd7 affects eye and heart development.

(A–B) Representative images of eye phenotypes induced by injection of chd7-MO in zebrafish embryos (B) compared with control embryos (A) at 72 hpf. Lateral view with anterior to right. Chd7 morphants had a reduced ocular size. Chd7-MO-injected zebrafish exhibited cardiac anomalies such as dysmorphic heart and tube-like heart shape (D) compared with control embryos (C). Insets in (C) and (D) represent an illustration of the heart phenotype in control or chd7 morphant embryos, respectively. (E–F) Bar graphs illustrating the prevalence of eye (E) and heart (F) phenotypes in wild-type (white bar), chd7-MO (black bar), control-MO-injected embryos (grey bar) and mRNA rescue (dark grey bar). ***<0.001, *<0.01. ***<0.001, *<0.01.

Figure Data

Phenotype details

Acknowledgments

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