Fig. 6
Phenocopy and rescue of mok phenotype. Transverse sections through retinae stained with YoPro to visualize cell nuclei (green) and the Zpr-1 antibody to visualize photoreceptors (red) at 4 dpf. In each panel, genotype is indicated in the upper right corner. Captions below indicate reagents that were injected into embryos to test their impact on photoreceptor survival. (A) Morpholino knockdown of mok function in wild-type larvae produces photoreceptor loss. (B) A control morpholino does not affect the photoreceptor cell layer. (C) GFP transcript does not affect photoreceptor survival in mokm632 mutant embryos. (D) The injection of mok transcript into homozygous mokm632 mutant embryos dramatically improves photoreceptor survival. Asterisks indicate the lens.