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Fig. 3

ID

ZDB-IMAGE-111207-3

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Ab1-en

Publication

Jurynec et al., 2008 - Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle

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Figures for Jurynec et al., 2008

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Fig. 3

Ryanodine receptors and SepN have similar functions in muscle formation. (A–D) Expression of ryr1a and ryr3 transcripts in 15-somite (A and B) and 24 hpf (C and D) embryos. (E–H) Expression of the myogenic lineage genes, myoD and α-cardiac actin, is greatly reduced in the adaxial cell population of ryr1a; ryr3 double morphants. (I–L) 4D9⁺ slow muscle pioneer fiber nuclei and (M–P) F59⁺ slow muscle fibers are reduced in number and irregularly shaped in 24-hpf embryos depleted for RyR1a, RyR3, or both RyRs. (A) Dorsal view, rostral up. B–D and I–P, lateral views, rostral left. (E–H) Dorsal views, rostral left.

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Expression / Labeling details

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA