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ZIRC
ZFIN ID: ZDB-GENE-041001-165
Gene Name: ryanodine receptor 3
Gene Symbol: ryr3    Nomenclature History

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Previous Name: si:ch211-189g6.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity; calcium-induced calcium release activity; and ryanodine-sensitive calcium-release channel activity. Involved in smoothened signaling pathway. Predicted to localize to several cellular components, including the Z disc; endoplasmic reticulum; and sarcolemma. Is expressed in Kupffer's vesicle; brain; musculature system; neurons; and somite. Orthologous to human RYR3 (ryanodine receptor 3).
Genome Resources: Alliance (1),  Gene:561350 (1),  Ensembl(GRCz11):ENSDARG00000071331 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013845Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021515Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa956 Point Mutation Unknown Splice Site ENU
    sa7471 Point Mutation Unknown Missense ENU
    sa9285 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9447 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • z45 Small Deletion Exon 6 Frameshift, Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ryr3 N/A 4
    TALEN1-ryr3 2
    DISEASE ASSOCIATED WITH ryr3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ryr3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process smoothened signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 22)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ryr3-201 (1)    Ensembl 16368
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ryr3 No data available
    MARKER RELATIONSHIPS
    ryr3 Contained in: [BAC] CH211-38E16 (1) (order this), CH211-189G6 (1) (order this), DKEY-81B15 (1) (order this)
    ryr3 Encodes: [EST] eu1589 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009294773 (1)
    Genomic GenBank:BX248136 (1) 222316 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IA72 (1) 4987 aa
    Sequence Clusters UniGene:151677 (1)
    Sequence Information (all 38)
    ORTHOLOGY for ryr3 ( Chr: 20 )
    CITATIONS (42)