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Fig. 1 etv5b and pea3 expression is reduced in ext2 mutants. Lateral view (left panels) and dorsal view (right panels) of etv5b (A-D, M-P) and pea3 (E-L) expression in 38 hpf ext2 mutants (C, D, G, H, K, L, O, P) and WT embryos (A, B, E, F, I, J, M, N). (I-P) Embryos treated with 8 μM SU5402 3 h prior to fixation. Note that pea3 expression in WT embryos is only marginally affected by the inhibitor (compare E-F with I-J) while pea3 expression is almost completely inhibited by the same treatment in ext2 mutants (compare G-H with K-L). The arrows label the MHB.
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Full text @ BMC Dev. Biol.