ZFIN Image: Follo et al., 2011, Fig. 8

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Figure Caption

Fig. 8

Immunofluorescence staining of microvilli in the eye of zebrafish following cathepsin D knock-down and rescue.

Immunofluorescence staining of α-actin (red) in eye sections derived from 4 dpf micro-injected larvae (CTRL = control injections; S-MPO = splicing morpholino; T-MPO = translation morpholino; RESCUED = translation morpholino plus 200 pg/egg of mutant CD mRNA). Nuclei are stained with DAPI (blue). The arrow points to microvilli of RPE cells. Note the absence of this structure in T-MPO zenbrafish. The photoreceptor cell (PRC) layer is indicated by curly brackets. Scale bar is 10 μm. Images representative of five (three for Rescued) independent experiments.

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Acknowledgments

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