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Fig. 7 Response of sox3 to elevated Fgf signaling. Expression of sox3 at 14 hpf in a control embryo (A), fgf24 morphant (B) and hs:fgf8 transgenic embryo (C). The lateral edges of the prospective epibranchial domain are indicated (dashed lines). All embryos were heat shocked at 11 hpf.
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Reprinted from Developmental Biology, 351(1), Padanad, M.S., and Riley, B.B., Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24, 90-98, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.