IMAGE

Fig. S7

ID
ZDB-IMAGE-110407-22
Source
Figures for Kim et al., 2011
Image
Figure Caption

Fig. S7 Mild ER stress increases TORC1 signaling in tsc2vθ242/b>+ zebrafish. Wild-type and tsc2vu242/+ siblings were treated with tunicamycin (Tn) (B,C,E,F). Untreated wild-type (A) and tsc2vu242/+ heterozygous zebrafish at 8 dpf (D) had minimal TORC1 activity. Markedly increased TORC1 signaling was seen with 200 ng/ml of Tn tsc2vu242/+ heterozygous zebrafish (E) compared to Tn treated wild-type (B). Treatment of both tsc2vu242/+ heterozygous zebrafish (F) and wild-type (C) zebrafish with 400 ng/ml of Tn led to increased TORC1 signaling evidenced by phospho-S6 (Ser235/236) staining. L, liver. Scale bar equals 100 μm.

Acknowledgments
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