ZFIN Image: Tittle et al., 2011, Fig. S5

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Figure Caption

Fig. S5 uhrf1 and dnmt1 are expressed in proliferative regions of the lens and retina at 5 dpf. In situ hybridization of uhrf1 sense (A) and antisense (B,C) and dnmt1 sense (D) and antisense (E,F) riboprobe on wild-type embryos at 5 dpf. No expression was detected in sense controls (A,D). Dorsal (B,E) and lateral (C,F) whole mount images demonstrate that uhrf1 and dnmt1 transcripts are present in both the ciliary marginal zone of the retina and in the proliferative germinative zone of the lens epithelium (which resembles a ring around the anterior lens when viewed in whole mount, arrows in C and F). Scale bars are 100 μm.

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Expression / Labeling details

Acknowledgments

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Reprinted from Developmental Biology, 350(1), Tittle, R.K., Sze, R., Ng, A., Nuckels, R.J., Swartz, M.E., Anderson, R.M., Bosch, J., Stainier, D.Y., Eberhart, J.K., and Gross, J.M., Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens, 50-63, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.