IMAGE

Fig. 4

ID

ZDB-IMAGE-110111-4

Genes

EGFP

Publication

Gjini et al., 2011 - Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity

All Figures

Figures for Gjini et al., 2011

Image

Figure Caption

Fig. 4 tie-2 mutants develop normal blood and lymphatic vasculature. (A) Confocal microscopy of trunk vessels in 5-day-old wild-type (Ai) and tie-2 mutant (Aii) embryos in the Tg(fli1:EGFP) background. Loss of Tie-2 protein does not affect blood and lymphatic vessel formation (Aii,iv) in zebrafish as compared to the wild-type blood (Ai) and lymphatic (Aiii) vessel development. (B) A test for functionality of the thoracic duct shows dye uptake in both wild-type siblings (Bi) and tie-2 mutants (Bii). Angiographies were performed in Bi and Bii to highlight the dorsal aorta (DA) and PCV. ISV, intersegmental vessels; TD, thoracic duct; DLAV, dorsal longitudinal anastomotic vessel.

Figure Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.