IMAGE

Fig. 6

ID
ZDB-IMAGE-100506-7
Genes
Source
Figures for Nguyen et al., 2010
Image
Figure Caption

Fig. 6 Craniofacial phenotypes of leo1LA1186. (A, B, C, D) Alcian blue staining of wild-type (A, C) and leo1LA1186 embryos (B, D) at 3 days post fertilization. Leo1LA1186 exhibit severe craniofacial defects including absence of the ethmoid plate from the anterior neurocranium and complete loss of pharyngeal arches. (A, B) Lateral view. (C, D) Ventral view. ANC, anterior neurocranium; t, trabecular cranii; m, mandibular arch; h, hyoid arch; P3–7, pharyngeal arches 3–7. (E, F, G, H) Tbx1 and endothelin-1 (edn-1) expression patterns in the pharyngeal arch epithelium and mesenchymal core are indistinguishable between wild-type embryos (E, G) and leo1LA1186 mutants (F, H) at 27 hpf.

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 341(1), Nguyen, C.T., Langenbacher, A., Hsieh, M., and Chen, J.N., The Paf1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish, 167-175, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.