ZFIN Image: Santoro et al., 2009, Fig. S3

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Figure Caption

Fig. S3 hands-off, but not cloche, mutant larvae show defective mural cell development. Seventy-two hpf larvae from wild-type crosses, or cloche (clos5) or hands-off (hans6) heterozygote incrosses analyzed for transgelin expression. In wild-type, transgelin expression identifies structures such as the dorsal aorta (long black arrows) and visceral smooth muscle (short black arrows). This expression is present in cloche mutants but missing in hands-off mutants. Images (a–c) lateral views, anterior to the left; (d–f) dorsal views, anterior to the left; (g–i) cross-sections at the level of the 1st2nd somite, and (j–m) cross-sections at the level of the 10–11th somite.

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Acknowledgments

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Reprinted from Mechanisms of Development, 126(8-9), Santoro, M.M., Pesce, G., and Stainier, D.Y., Characterization of vascular mural cells during zebrafish development, 638-649, Copyright (2009) with permission from Elsevier. Full text @ Mech. Dev.