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Fig. S5 Inhibitors of Bmp and Wnt signaling respond to ectopic Bmp signal. Transgenic and control embryos were heat shocked at 3 somites and fixed at 9 somites. In-situ hybridization demonstrates that ectopic Bmp signaling upregulates expression of noggin1 and noggin2. Expression of chordin may be very slightly downregulated. wif1 expression is reduced but not eliminated. It is shown in combination with pax2.1 staining, which does not change under these conditions.
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Reprinted from Developmental Biology, 329(1), Row, R., and Kimelman, D., Bmp inhibition is necessary for post-gastrulation patterning and morphogenesis of the zebrafish tailbud, 55-63, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.