ZFIN Image: Dowling et al., 2009, Fig. 6

Image

Figure Caption

Fig. 6 Increased PI3P levels in myotubularin morphant myofibers.

(A) Representative myofibers immunostained with anti-PI3P. Perinuclear staining of PI3P in myotubularin morphant myofibers is much more abundant than in control myofibers (arrows). There is also a modest increase in membrane localized PI3P (*). Scale bar = 10 mm. (B) Quantitation of PI3P immunofluorescence. PI3P intensity measured over a uniform perinuclear area (see methods for details) and was 83.7+/-7.8 pixels for control morphants and 135.5+/-3.3 for myotubularin morphants (3 trials; p = 0.0027). This represented a 1.6x increase in PI3P staining intensity.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.