Fig. 1

Fig. 1 Lateral views of wild-type and noi mutant embryos. (A) Wildtype embryo at 24 hours pf. (B) Schematic drawing of the structures seen in A. (C) Strong noi^tu29a mutant, which lacks MHB, tectum (asterisk) and cerebellum. (D) Weak noi^tb21 phenotype; a partially formed tectum is observed, the caudal end marked by the arrowhead. (E) A wild-type embryo at day 7. A homozygous mutant for noi^tu29a of the same age is seen in (F), showing severe oedema of the pericard and gut epithelium, causing delayed development. (G) Survival rates of different noi alleles. n=30 mutant embryos per allele were analyzed. The difference between the strong noi^tu29a allele and the weaker alleles is clearly visible. The mutants never feed and die within 2 weeks. c, cerebellum, di, diencephalon, epi, epiphysis, pros, prosencephalon, rh, rhombencephalon, tc, tectum, tg, tegmentum, v, ventricle.