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Fig. 1
Zebrafish Shp2 Is Conserved and Is Expressed Ubiquitously during Development
(A) Schematic representation of zebrafish Shp2 with two SH2 domains to the N-terminal side of the PTP domain. The overall sequence identity with human and mouse Shp2 is indicated. (B–F) In situ hybridization with a Shp2-specific antisense probe at various stages of development: (B) 8-cell stage, (C) 4 hpf, (D) shield stage, (E) 10 hpf, (F) 14 somite (14 s, 14 hpf), (G) 24 hpf, and (H) 3 dpf.
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