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Fig. 5 too few mutant embryos have reduced number of hypothalamic neurons. (A, B, and G, H) Ventral and (C–F) lateral views of wildtype (left) and too few mutant (right) embryos labeled with anti-TH antibody. (A–F) 2-day-old embryos showing reduced number of hypothalamic DA neurons but normal complement of postoptic DA and LC neurons. (G and H) 96-h fry showing that the reduction of hypothalamic DA neurons persist. Abbreviations: Hy DA, hypothalamic DA neurons; po, postoptic region; te, tectum, tg, tegmentum; Scale bar: 150 μm (A, B), 120 μm (C, D), and 60 μm (E–H).
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Reprinted from Developmental Biology, 208, Guo, S., Wilson, S.W., Cooke, S., Chitnis, A.B., Driever, W., and Rosenthal, A., Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons, 473-487, Copyright (1999) with permission from Elsevier. Full text @ Dev. Biol.