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Fig. S4b (K–M) Induction of wnt8 at 1 somite (10 hpf) resulted in inhibition of hhex expression at 24 hpf (39/51), while heat-shock at 10 somites (14 hpf) caused significant expansion of hhex (60/72). (N–P) Expression of pdx1 was diminished following wnt8 induction at both 1 (29/37) and 10 somites (14 hpf; 42/54).
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Reprinted from Developmental Biology, 320(1), Goessling, W., North, T.E., Lord, A.M., Ceol, C., Lee, S., Weidinger, G., Bourque, C., Strijbosch, R., Haramis, A.P., Puder, M., Clevers, H., Moon, R.T., and Zon, L.I., APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development, 161-174, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.