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Fig. S5
Morpholino mediated knockdown of itga7 or ilk causes retraction of the complete skeletal muscle cell.
A,B) 3D reconstructions of confocal images showing retracted muscle fibres with membrane localized eGFP (green) and f-actin (phalloidin stain in red). Muscle fibre retractions were induced by morpholino knockdown of itga7 (A) or ilk (B). Arrows indicate retracted muscle fibres.
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Reprinted from Developmental Biology, 318(1), Postel, R., Vakeel, P., Topczewski, J., Knöll, R., and Bakkers, J., Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex, 92-101, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.