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Fig. S2
Shp2 and Wnt5 Knockdown Acts Synergistically to Induce a Hammerhead Phenotype at 4 dpf
Shp2-MO and Wnt5-MO were injected at 50% of their normal concentration. By themselves, these injections did not induce defects (compare to morphology at 4 dpf with WT, noninjected control). Coinjection of Shp2-MO and Wnt5-MO did induce the hammerhead phenotype at 4 dpf. Note the blunted face and the increased distance between the eyes in the double-injected embryo (Shp2 + Wnt5).
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