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Fig. 11 ERK activation in Fgf19 MO2-injected embryos. ERK1/2 activation was detected by whole mount immunohistochemistry in wild-type embryos (a) and embryos injected with Fgf19 MO2 (b) at 22 hpf. (a) In wild-type embryos, ERK1/2 activation was detected in the nasal retina and lens. (b) In Fgf19 MO2-injected embryos, ERK1/2 activation was suppressed in the nasal retina and lens. Lateral views with anterior to the left and dorsal to the top.
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Reprinted from Developmental Biology, 313(2), Nakayama, Y., Miyake, A., Nakagawa, Y., Mido, T., Yoshikawa, M., Konishi, M., and Itoh, N., Fgf19 is required for zebrafish lens and retina development, 752-766, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.