ZFIN Image: Bit-Avragim et al., 2008, Fig. 5

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Figure Caption

Fig. 5 aPKC kinase catalytic activity prevents nuclear accumulation. Images are reconstructions of confocal Z-stack sections imaged on late gastrula stage whole mounts. Anti aPKC (A,B,D,E) and anti-Myc (C) stainings are false-colored. A: Endogenous aPKC localization in EVL cells is mostly at the outer cell membrane whereas (B) weak levels of wt protein are also detectable throughout the cytoplasm and nuclei of DL cells. C: HisMyc-tagged aPKCi^D57A within EVL cells localizes to the cytoplasm and is complete absent from outer cell membranes or nuclei. D: aPKCi^KD strongly localizes to the nuclei of EVL and (E) DL cells. All images are apical views onto the tissue.

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Expression / Labeling details

Acknowledgments

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